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Silphium (probably of the genus Ferula) was a plant that grew in the area of Cyrene, present day Libya, and was widely renowned as a spice, medicinal herb and perfume ingredient throughout the empires of the classical antiquity. It was praised by Greek philosophers and writers, as well as Roman emperors and cookbook authors.
There were many attempts to cultivate Silphium, but they inevitably failed. It would only grow wild in a limited area of the north African coast. This, in combination with its qualities as seasoning and medicine made Silphium the most valuable spice in the world, outshining both saffron and cinnamon. The demand for Silphium eventually became so overwhelming that it was harvested to extinction, and the taste and smell of the once greatest spice in the world were lost in time.